2100nm CTH:YAG(Cr,Tm,Ho:YAG) laser used for laser lithotripsy. Currently, several different types of lasers are used for the clinical application of laser lithotripsy. Lithotripsy works by physically absorbing the continuous pulses of laser energy to produce a photothermal effect, which is superior to other lasers in terms of performance and safety, avoiding the disadvantages of conventional lithotripsy, considering the high energy density of the laser, which can easily cause damage to the body. Its main advantages are the use of the fiber’s flexible nature in conjunction with a flexible nephroscope and the high efficiency of stone removal. In addition to lithotripsy, the CTH:YAG laser can be used to treat local soft tissue lesions, while its thermal radiation has an antibacterial effect.